Clinicians take a human tissue sample

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

NCCR AntiResist

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

NCCR AntiResist

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

NCCR AntiResist

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

Revitalizing antibiotic discovery by a patient-centered paradigm shift

Antibiotics are powerful and indispensable drugs to treat life threatening bacterial infections, such as sepsis or pneumonia. Antibiotics also play a central role in many other areas of modern medicine, in particular to protect patients with a weakened immune system during cancer therapies, transplantations or surgical interventions. These achievements are now at risk, with the fraction of bacterial pathogens that are resistant to one or more antibiotics steadily increasing.

The discovery and development of novel antibiotics faces complex societal, economic, technological and scientific challenges. The declining pipeline for novel antibiotics and increasing resistance to existing drugs gradually reduces the options clinicians have to treat bacterial infections.

NCCR AntiResist

The National Center of Competence in Research AntiResist aims to bring about a paradigm shift in antibiotic research with an interdisciplinary approach that assembles a Swiss-wide network of research groups from the fields of clinical research, biology, chemistry, computation, engineering and pharmacology.

The research program is structured into three four-year phases covering strategically and dynamically evolving milestones. Research activities center around a better understanding of pathogen physiology in patients; developing axenic and tissue-based model systems mimicking patient environments; and engineering of novel screening platforms for the next generation of antibiotics.

NCCR AntiResist is funded by the Swiss National Science Foundation, and the home institution is the University of Basel.

Watch below our short video produced by the University of Basel.

News and Events

Happy Pride

NCCR AntiResist celebrates Pride Month this June!  Go to our Equal Opportunities, Diversity and Inclusion page for more information.

 

"Einblicke Biozentrum" Lecture

Join us June 28th at 7:00 PM at the Biozentrum in Basel for Prof. Christoph Dehio's public lecture "Antibiotikaresistenz - Wege aus der Krise".  This event is in German and open to all.  More information can be found at the Biozentrum webpage here

We're Hiring

Come join our team! We have multiple positions open. Full job descriptions can be found on our Open Positions page here

Spring School on Bioinformatics and Computational Approaches in Mircobiology

Together with SIB and NCCR Microbiomes, AntiResist is organizing a Spring School, May 8 to 13, 2022 in Nottwil, Switzerland. The goal of this joint School is to provide PhD students and postdocs with theoretical and mostly hands-on knowledge on selected topics about microbiome and antibiotic resistance. Application deadline is April 15. All the information and a detailed description of the 4 proposed mini projects can be found here.

UniBâle Podcast with Christoph Dehio, Director NCCR AntiResist

Christoph Dehio, speaks with Prime News' Oliver Sterchi about the antibiotic resistance problem, its threat to world health, and AntiResist's new approach to antibiotic research on the UniBâle Podcast. Listen to the 25 minute podcast, "Antibiotikaresistenzen - eine Gefahr für die Weltgesundheit", in German, here. Other podcasts and Primenews articles to the podcasts can be found at https://primenews.ch/podcast/unibale.