Clinicians take a human tissue sample

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

NCCR AntiResist

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

NCCR AntiResist

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

NCCR AntiResist

NCCR AntiResist

New approaches to combat antibiotic-resistant bacteria

Revitalizing antibiotic discovery by a patient-centered paradigm shift

Antibiotics are powerful and indispensable drugs to treat life threatening bacterial infections, such as sepsis or pneumonia. Antibiotics also play a central role in many other areas of modern medicine, in particular to protect patients with a weakened immune system during cancer therapies, transplantations or surgical interventions. These achievements are now at risk, with the fraction of bacterial pathogens that are resistant to one or more antibiotics steadily increasing.

The discovery and development of novel antibiotics faces complex societal, economic, technological and scientific challenges. The declining pipeline for novel antibiotics and increasing resistance to existing drugs gradually reduces the options clinicians have to treat bacterial infections.

NCCR AntiResist

The National Center of Competence in Research AntiResist aims to bring about a paradigm shift in antibiotic research with an interdisciplinary approach that assembles a Swiss-wide network of research groups from the fields of clinical research, biology, chemistry, computation, engineering and pharmacology.

The research program is structured into three four-year phases covering strategically and dynamically evolving milestones. Research activities center around a better understanding of pathogen physiology in patients; developing axenic and tissue-based model systems mimicking patient environments; and engineering of novel screening platforms for the next generation of antibiotics.

NCCR AntiResist is funded by the Swiss National Science Foundation, and is based in the Biozentrum at its home institution of the University of Basel.

Watch below our short video produced by the University of Basel.

News and Events

Image of open data connections with title Open Research Data

Open Research Data Events

NCCR AntiResist together with six other NCCRs is organising a series of three joint NCCR meetings aimed at students and researchers on open research data, to be held in Zurich (April 28)Lausanne (May 8), and Basel (June 2), featuring presentations and practical workshops by experts and researchers who have developed methods for practicing various aspects of open research data.Registration is now open and free. You do not need to be working on an NCCR project to attend. Flexible booking is available for morning lectures or afternoon workshops, and for single or multiple days. See the event program to learn more.

Spring 2023 Academic Semester

We look forward to an exciting semester ahead teaching and researching on antibiotic resistance. Our NCCR AntiResist community is invited to attend the hybrid seminar series on Monday nights. See more details on our Seminars page or view the list of speakers here.