Publications 2025

Journal Articles          Review Articles          Book Chapters          Preprints


Journal articles


Mechanisms of Pseudomonas aeruginosa resistance to type VI secretion system attacks

Authors: Tejada-Arranz, A., Plack, A., Antelo-Varela, M., Kaczmarczyk, A., Klotz, A., Jenal, U., and Basler, M.

Published in: Nature Communications 2025

DOI: 10.1038/s41467-025-65777-x

Preprint: 10.1101/2024.10.26.620397


Reemergence of Brucella abortus, Israel, 2021

Authors: Bardenstein, S., Grupel, D., Even-Tov, B., Motro, Y., and Moran-Gilad, J.

Published in: Emerging Infectious Diseases 2025

DOI: 10.3201/eid3104.241003


Limited impact of Salmonella stress and persisters on antibiotic clearance

Authors: Fanous, J., Claudi, B., Tripathi, V., Li, J., Goormaghtigh F., and Bumann D.

Published in: Nature 2025

DOI: 10.1038/s41586-024-08506-6

Read more about the article:  Research Briefing: Why a standard method overlooks the real reason some antibiotics fail


A human metabolic map of pharmacological perturbations reveals drug modes of action

Authors: Schuhknecht, L., Ortmayr, K., Jänes, J., Bläsi, M., Panoussis, E., Bors, S., Dorčáková, T., Fuhrer, T., Beltrao, P., and Zampieri, M.

Published in: Nature Biotechnology 2025

DOI: 10.1038/s41587-024-02524-5


Amoxicillin Concentrations in Samples of Musculoskeletal Infections

Authors: Erdmann, J., Kuehl, R., Morgenstern, M., Bumann, D., Clauss, M., Khanna, N., and Rentsch, K.M.

Published in: Helvetica Chimica Acta 2025

DOI: 10.1002/hlca.202400178


Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation

Authors: Vaidya, S., Saha, D., Rode, D.K.H., Torrens, G., Hansen, M.F., Singh, P.K., Jelli, E., Nosho, K., Jeckel, J., Göttig, S., Cava, F. and Drescher, K.

Published in: Nature Microbiology 2025

DOI: 10.1038/s41564-024-01886-5


Review articles


Comment

Decoding host-microbe interactions with engineered human organoids

Comment

Authors: Lucas A Meirelles and Alexandre Persat

Published in: EMBO Journal 2025

DOI: 10.1038/s44318-025-00387-3


Book chapters



Preprints


A ratiometric pH sensor for Gram-positive and Gram-negative bacteria

Authors: Kossmann, D., Iizuka, A., Khanna, N., Rivera-Fuentes, P.

Preprint: BioRxiv

Publication date: September 9, 2025

DOI: 10.1101/2025.09.09.675137


Microgeography of staphyloccoci in human tissue explains antibiotic failure

Authors: Tripathi, V., Morin, B., Antelo Varela, M., Loriol, A.A., Kurg, K., Jakonia, S., Ehsan, A., Herbert, S., Ferrand, A., Sauteur, L., Marro, F.C., Henselmann, N., Künnecke, J., Estermann, F., Strenger, K., Iizuka, A., Woischnig, A.-K., Claudi, B., Söderholm, S., Keller, P.M., Baumhoer, D., Bock, T., Jantarung, K., Riviera Fuentes, P., Meylan, S., Morgenstern, M., Clauss, M., Khanna, N., Kuehl, R., Bumann, D.

Preprint: BioRxiv

Publication date: September 12, 2025

DOI: 10.1101/2025.09.12.675782


Strain-resolved CRISPRi-Seq reveals conserved antibiotic vulnerabilities in Staphylococcus aureus

Authors: Mazzuoli, M.-V., Burnier, J., Schmid, A., Martin, L., Janssen, A., Gallay, C., Zinkernagel, A.S., Veening, J.-W

Preprint: BioRxiv

Publication date: October 13, 2025

DOI: 10.1101/2025.10.13.682098


A bioengineered human urothelial organoid model reveals the urine-urothelium interplay in tissue resilience and UPEC recurrence in urinary tract infections

Authors: Paduthol, G., Nikolaev, M., Sharma, K., Blanc, J., Tomasek, K., Schlunke, L.I.E., Borgeat, V., Ambrosini, G., Kolotuev, I., Clerc-Rosset, S., Gjorevski, N., Knott, G.W., Lütolf, M.P., Thacker, V.V., McKinney, J.D.

Preprint: BioRxiv

Publication date: October 30, 2025

DOI: 10.1101/2025.10.28.685030


Genome-scale CRISPRi profiling reveals metabolic vulnerabilities of uropathogenic Escherichia coli in human urine

Authors: Ortelli, M., Prakapaité, R., Müller, A., Miele, S.A.B., Fino, C., Klimke, S., Tschudin-Sutter, S., Jenal, U., De Bento Flores, C.E., Bikard, D., Dehio, C.

Preprint: BioRxiv

Publication date: October 31, 2025

DOI: 10.1101/2025.10.31.685768


Perfusable 3D human urothelial model for real-time analysis of bacterial infection dynamics and therapeutic interventions

Authors: Kurmashev, A., Sorg, I., Boos, J.A, Grassi, L., Sellner, B., Fino, C., Girgin, M., Mueller, A.L, Klimke, S., Tschudin-Sutter, S., Hierlemann, A., and Dehio, C.

Preprint: BioRxiv

Publication date: November 13, 2025

DOI: 10.1101/2025.11.12.687885